Considering that eosinophils play a prominent pro-inflammatory role in allergic airway inflammation, and noting that other authors have recently described the SOCS3 expression in different cellular types, such as macrophages and microglia [30], we determined if blood eosinophils are able to express SOCS3 and SOCS5 at the protein level and thus contribute to regulate cytokine balance in NAEB and asthma, conditions in which eosinophils are one of the most important cell types. Here, SOCS5 is linked to asthma.