IL1A and cancer: Nonetheless, clinical trials showed that recombinant human IL-1α treatment accelerated platelet recovery during chemotherapy and reduced carboplatin-induced thrombocytopenia in patients with recurrent OC [34], as well as in patients with ovarian and other cancer types (gastrointestinal, breast, melanoma, lung, head and neck, sarcoma, and prostate) who did not receive concomitant chemotherapy [35].