The ARHGEF16 promoter does show hypermethylation on Infinium Methylation arrays (Illumina, San Diego, USA), on 68 anaplastic oligodendrogliomas and oligoastrocytomas; PF, manuscript in prep) and is correlated with loss of 1p and 19q (p = 0.035, Fisher exact test). The gene discussed is ARHGEF16; the disease is oligodendroglioma.