The immunophenotype of the neoplasm was the following: AE1/AE3:+++, CK7:+++, CAM5.2:+++, polyclonic CEA:++, CK34Be12:+, CK18:+, synaptophysin:+++, NSE:+, polyclonic Ca 19-9:−, Ki67:+ in 30% of cancer cells, P53:+ in 80% of cancer cells, Cerb2: expressed in <10%, EGFR:+ in 30%, and Ckit:−. The gene discussed is ERBB2; the disease is cancer.