On the other hand there was a trend for a reduced incidence of hypoglycaemia in the aforementioned meta-analysis, the reduction not reaching significance with α-glucosidase inhibitors (RR 0.60; 95%CI 0.08-4.56), and DPP-4 inhibitors (RR 0.67; 95%CI 0.30-1.50). This evidence concerns the gene DPP4 and Hypoglycemia.