INS and type 2 diabetes mellitus: In order to identify the association between a set of inflammatory markers and acute phase proteins (sCRP, amyloid-A, and VDBP) and the serum biochemical indices of predisposition to T2DM (fasting insulin and glucose, HDL-C, LDL-C, and TGs, as well as BMI), a cross-correlation analysis was carried out between these factors as shown in Figure 1.