Our study provides for the first time a significant correlation between TNF-α expression and the expression of putative TNF-α-inducible NF-κB target genes (as identified in microvascular endothelial cells) in human breast tumors (Table 10). The highest correlation between TNF-α and NF-κB related genes was observed for ERalpha negative-, as compared to ERpositive- breast tumors. Here, TNF is linked to breast neoplasm.