MAGEA11 and prostate neoplasm: MAGE-A11 expression is regulated by DNA methylation status: in castration-recurrent prostate tumors, MAGE-A11 is upregulated, correlating with hypomethylation of discrete CpG sites adjacent to the transcriptional start site of the gene, by contrast, the methylation status of other regions of the MAGE-A11 promoter CpG island does not correlate with gene expression [24].