Serous ovarian cancer cell lines OVCA420 and OVCA429 were growth inhibited in hypoxia (1% O2) and glucose deprivation (HG) conditions and the transfection with siRNA targeting HIF1 α and ENO1 has limited effect on further growth inhibition compared to the control transfected cells (Figure 3c and d). This evidence concerns the gene HIF1A and ovarian cancer.