As previously published, we found that loss of Arf and Pten, but not Ink4a, shortened tumor latency and increased incidence of murine GBMs, histologically defined by the presence of microvascular proliferation and pseudopalisading necrosis (Figure 2a; Figure S4a,b) [3], [36], [37]. The gene discussed is CDKN2A; the disease is neoplasm.