PROM1 and cancer: We observed that increased proliferating cancer stem/progenitor cells (Fig. S2a), and expanded cancer stem/progenitor populations, defined as p63+/CK5+ double positive (Fig. S2b), Sca-1+ (Fig. S2c), or CD133+ (Fig. S2d), were significantly different in pes-ARKO TRAMP comparing with the Wt TRAMP.