Moreover, expression of CYP1A1, 1B1 and 3A4 enzymes was found to be induced by treating glioblastoma U87MG, adenocarcinoma MCF-7 and neuroblastoma UKF-NB-4 cells with ellipticine (Martínková et al., 2009; Stiborová et al., unpublished results). The gene discussed is CYP1A1; the disease is adenocarcinoma.