RECQL and glioblastoma: To test the role of RECQ1 in glioblastoma cell growth and proliferation, we compared the colony forming properties of two different glioblastoma cell lines (T98G and U-87), and normal human IMR-90 fibroblasts, transiently transfected with RECQ1-specific siRNAs versus cells transfected with a luciferase siRNA duplex, as control (Figure 5).