In particular, the RECQ1 positive cells of 48 out of 63 glioblastoma speciemen present in the TMA showed a strong nuclear positivity characterized by a staining nuclear intensity of 3+, while most of the cells positive for RECQ1 in the perilesional tissues were characterized by a weaker staining intensity of 2+ (Figure 4D). This evidence concerns the gene RECQL and glioblastoma.