ADIPOQ and hydrops fetalis: We have recently observed that a shorter duration (8 instead of 14 weeks) of a certain type of HF diet with reduced levels of ω-3 and, particularly, ω-6 PUFA fatty acid precursors, and higher cholesterol levels, instead decreases hepatic FAS and ACC1 expression in mice, with no change in SREBP1 expression nor in plasma glucose, non-esterified fatty acids (NEFA) and adiponectin levels [30].