XRCC1 and Erythema: Finally, no correlation was found between acute toxicity and mut/het RAD51. Multivariate analysis confirmed the mean dose to WB (p = 0.002), the presence of mut/het XRCC1 Arg194Trp or wt XRCC3 Thr241Met (p = 0.006) and the presence of mut/het XRCC1 Arg194Trp or wt GSTA1 (p = 0.031) as predictors of erythema.