Known NRF2 target genes were also altered only in the PD cells (GSTM5[30], USP14[31]), or only in Control cells (AKR7A2[32], [33], ATF4[31], HMOX1[34], SQSTM1[35], MGST1 and MGST3[36]). This evidence concerns the gene SQSTM1 and Parkinson disease.