TXNRD1 and Parkinson disease: Many genes in each group are established NRF2 target genes, and included NQO1 and GCLM mRNAs (consistent with our qRT-PCR results) and other known NRF2 targets such as MAFG[23], KEAP1[24], GSR[25], EPHX1[26], TXNRD1[27], PRDX1[28] and TXN[29], all of which were induced in response to L-SUL treatment in both PD and Control hONS cultures.