We have previously shown colocalization of ezrin in adherens junctions with N-Cadherin but no expression of E-Cadherin in HPV 18 containing HeLa cervical carcinoma cells, as well as the requirement for Rac1, phosphatidylinositol-4-phosphate 5-kinase (PIPKα) and RhoA for this localization [58]. The gene discussed is EZR; the disease is cervical carcinoma.