Figure 2A shows that mean IgG antithrombin levels were significantly increased in the 2 groups of patients who were positive for serum aPL (24.1 AU in the APS group and 31.3 AU in the SLE/aPL+ group, compared with 14.6 AU in the SLE/aPL− group and 13.6 AU in the healthy controls). There were statistically significant differences between the APS group and the healthy controls (P < 0.05), between the SLE/aPL+ group and the healthy controls (P < 0.01), and between the SLE/aPL+ group and the SLE/aPL− group (P < 0.01). The gene discussed is FASLG; the disease is autoimmune polyendocrinopathy.