7Lesions caused by the human papillomavirus (HPV): as with oral candidiasis, HPV lesions (papillomas, focal epithelial hyperplasia or condyloma acuminatum) are more frequent when CD4 cell counts are lower;9 however, as opposed to oral candidiasis and pilous leukoplakia, HPV infection rates did not decrease following antiretroviral therapy.5, 11 The most common type is type 32.17 This evidence concerns the gene CD4 and hyperplasia.