Respiratory infection is one of the main causes of mortality and morbidity in AIDS patients.17, 18, 19, 20 Lymphoid tissues in IgA-secreting mucosa are the main local protective mechanism for the respiratory tract; activation of these tissues is the goal of vaccines aiming at conferring immunity in upper airways to prevent respiratory infection.10, 11, 13. The gene discussed is CD79A; the disease is respiratory tract infectious disorder.