NFKB1 and colorectal carcinoma: As shown in Table 3, compared with the NFκB1-94 del/del and NFκB1IA 2758AA+AG genotype, one variant combined genotype carriers who were <60 years of age had a higher risk of CRC (OR = 1.57; 95% CI = 1.04–2.38) (P<0.05).