Several association studies have reported that the NFκB1 and NFκBIA polymorphisms is related to the development of inflammatory and other diseases including ulcerative colitis, Graves' disease, and diabetes mellitus, and susceptibility to tumors including melanoma, bladder cancer and CRC in different ethnic groups [32], [36], [45], [46], [47], [48]. This evidence concerns the gene NFKB1 and diabetes mellitus.