NFKBIA and cancer: To test this hypothesis, we genotyped the NFκB1-94 insertion/deletionATTG and NFκBIA 2758A>G polymorphisms in our ongoing hospital-based case–control study of CRC in a southern Chinese population, and further performed luciferase assays and Western blotting analysis to identify whether genetic variants in NFκBIA alter its gene expressions and functions and thus cancer risk.