Additionally, the CD1 system may play a role in human autoimmune diseases, since CD1b-restricted T cells recognizing self glycolipids such as gangliosides and sulfatide were isolated from multiple sclerosis patients [16], and autoreactive CD1c-restricted T cells from lupus patients were found to promote IgG secretion by B cells [17]. The gene discussed is CD1B; the disease is multiple sclerosis.