Among them, some have been confirmed in previous studies, such as delta-like 1 (DLL1) and jagged 1 (JAG1) genes, which are involved in NOTCH signaling pathway [53], B-cell CLL/lymphoma 2 (BCL1), which impacts outcomes after sever traumatic brain injury [54], and mitogen-activated protein kinase kinase 1 (MAP2K1), which is aberrantly expressed in the brain of suicide subjects [55]. The gene discussed is MAP2K1; the disease is injury.