Recently, a multistage genome-wide association study (GWAS) of breast cancer identified a new breast cancer susceptible locus at 1p11.2 (the marker SNP: rs11249433) in populations of European descent, which resides in a large linkage disequilibrium (LD) block neighboring NOTCH2 and FCGR1B[4]. Here, NOTCH2 is linked to breast carcinoma.