In order to determine the clinical relevance of α-SMA, palladin, uPARAP/Endo 180 and EDA in RCCs, and hence their possible usefulness as prospective markers, we analyzed their levels of expression in the stroma of 53 normal and RCC surgical samples that constituted a tumor microarray (TMA) described in Table 1. This evidence concerns the gene MRC2 and renal cell carcinoma.