The locus associated with total WBC count on chromosome 6p21 contains genes associated with follicular lymphoma (CHCG22), progression of HIV-1 infection (CDSN, PSORS1C1 and PSORS1C2) and psoriasis (CCHCR1, PSORS1C1 and PSORS1C2) [67], [68], [69]. This evidence concerns the gene CDSN and HIV-1 infection.