T cells cultured alongside in the absence of DCs, but in the same amounts of live-HSV-2 used to treat the DCs (0.2 MOI), did not show evidence of infection (Figure S5 A), alteration of viability status (not shown) or changes in the expression of α4β7 (Figure S5 B) 5 days p.i. However, as previously reported [36], T cells treated with a higher inoculum are susceptible to HSV-2 infection, as demonstrated by the detection of ICP-8+CD4+ T cells after exposure to 5 MOI of HSV-2 (Figure S5 A). The gene discussed is CD4; the disease is infection.