The GSTM1 null/GSTT1+ was significantly higher in POAG patients than in controls (OR=2.4; 95% IC: 1.16–4.9; p=0.016) and the association of genotypes GSMT1 null and GSTP1 Ile/Val or Val/Val was also significant (OR=2.7; 95% CI: 1.07–6.74; p=0.033). Here, GSTP1 is linked to open-angle glaucoma.