Genes thus far implicated in CCO include paired box 6 (PAX6), pituitary homeobox 2 (PITX2), forkhead box C1 (FOXC1), forkhead box E3 (FOXE3), beta 1,3-galactosyltransferase-like (B3GALTL), and keratocan (KERA), indicating the genetic heterogeneity of the condition (Table 1). This evidence concerns the gene PAX6 and central core myopathy.