In the multivariate analysis examining the relationship between ethnicity and adiponectin levels (Table 3 and Additional File 3: Table S1), Latino ethnicity was the strongest negative predictor of both total (-4.7; 95% CI -6.7, -2.8; p < 0001) and HMW (-1.8; 95% CI -2.9, -0.8; p = 0.001) adiponectin, independent of all other variables included in the model (age, gender, TZD use, Statin use, estimated GFR, diabetes status, and waist circumference/BMI). The gene discussed is ADIPOQ; the disease is diabetes mellitus.