Luciferase reporter assay indicated no such modulation by SNP rs3131703, polymorphic only in the Caucasian population, and MFSD2A mRNA levels in normal lung tissue of lung cancer patients showed no statistically significant association with rs3131703, thus excluding the candidacy of this SNP as a functional genetic element regulating MFSD2A promoter activity. This evidence concerns the gene MFSD2A and lung cancer.