TP53 and Familial prostate cancer: Others have proposed links between neurodegeneration/cancer and cell cycle regulation, DNA repair, response to oxidative stress [25], [26], aberrant wingless and proto-oncogene Int-1 (Wnt) signaling [27], glycogen synthase kinase 3 beta (GSK3β) regulation [28], modulation of tumor protein (TP53 or P53) expression [29], and perturbations of tau in AD and prostate cancer [30].