Finally, HIV-1 infection increased the sensitivity of DCs to die spontaneously (20±4% uninfected versus 31±6% in infected DCs) and after FasL-ligation (64±7% versus 31±6% in medium alone) but not to the binding of TRAIL (32±6%) (Figure 3B). The gene discussed is TNFSF10; the disease is HIV-1 infection.