IRGM and infection: Though the genotype of the recipient mouse had no discernable impact on NR1 cell proliferation based on CSFE dye dilution, we did observe a significant increase in the total number of NR1 cells in the iliac lymph node (Fig. 6A and 6B) and the uterus (Fig. 6C) of Irgm1/m3(-/-) mice on day 6 post-infection compared to Ifngr1-/- and wildtype mice.