A few data also suggest that EGP40 is functionally active in many tumors and is located at intercellular boundaries in many carcinomas, similar to its location in normal tissues.[3, 4] In view of its adhesion function and its presence only in epithelial tissue, the name Ep-CAM is correlated with proliferation, decreased cadherin-mediated adhesion and differentiation of the tumor cells. The gene discussed is EPCAM; the disease is neoplasm.