Furthermore, expression of high-risk HPV E6 has been linked to an increase in EGFR levels (Akerman et al, 2001), and changes in functional levels of the HPV E6/E7 proteins may alter the growth rate of cervical carcinoma cell lines by reducing the stability of EGFR at the posttranscriptional level (Hu et al, 1997). The gene discussed is EGFR; the disease is cervical carcinoma.