ANOVA and a subsequent Bonferroni post hoc test revealed significantly increased apoptotic rates for all transfection conditions (untransfected + unstressed vs. untransfected + in vitro ischemia, p < 0.0001; GFP siRNA + unstressed vs. GFP siRNA + in vitro ischemia, p < 0.0001; survivin siRNA + unstressed vs. survivin siRNA + in vitro ischemia, p = 0.0002). Here, BIRC5 is linked to ischemia.