We will discuss the primary findings of the study: the expression of MIF in the mouse brain is highly dynamic (1); the deletion of Mif in mice does not affect the expression of Th1/Th2 cytokines in the brain and serum (2), spleen weight (3), reactive astrogliosis (4) and number of CD74+ cells in the brain (5); after stroke. This evidence concerns the gene CD74 and stroke disorder.