CXCL1 and Stroke: In stroke patients, increased cerebrospinal fluid and/or circulating IL-1β, IL-6, IL-10, and CXCL-1 (CINC-1/IL-8), monocyte chemoattractant protein-1, and TNF-α concentrations have been reported [3], and IL-6 in particular identified as a predictor of stroke outcome [9].