As this recruitment may lead to atherosclerosis, MCP-1 was measured in patients with or without CAD, and it was found to be elevated in the former group.27 Adipocytes also secrete resistin, which stimulates inflammatory cytokine production, as well as decreasing endothelial cell adhesion molecule (iCAM-1, vCAM-1, Ccl-2) production, which may promote atherosclerosis.28 The role of resistin in insulin resistance is still unclear.29,30. This evidence concerns the gene CCL2 and Insulin resistance.