Colchicine treatment is known to reduce the frequency and intensity of attacks in FMF, and it apparently also lowers the level of circulating fibrin, thereby reducing coagulation and later fibrinolysis.13 Colchicine treatment also lowers levels of soluable E- and L-selectin in FMF and Behcet’s patients (26, 27) and was shown to diminish the qualitative expression of E-selectin on endothelium, and the quantitative expression of of L-selectin on neutrophils.28 Here, SELE is linked to familial Mediterranean fever.