F5 and beta-thalassemia intermedia: Among Lebanese sickle/β0-thalassemia patients, a high prevalence of thrombophilic mutations of FVL (42%), homozygous and heterozygous MTHFR C677T (59%), and prothrombin G20210A (8%) has been reported.51 In this report sickle-β-thalassemia patients were 5.24 and 4.39 times more likely to have FVL mutation as compared to the normal controls and thalassemia intermedia patients, respectively (p <0.05).