However, in this patient the presence of proteins C, S, antithrombin III, factor V Leiden (FVL), and prothrombin mutations as well as anticardiolipin antibodies were negative.20 Also, a 25-year-old French SCD patient with cerebral vein thrombosis and bilateral thalamic infarcts has been reported.21 Further, the report of Ozu et al22 indicated the occurrence of sinus thrombosis and thalamic infarcts in a 2-year-old child from Turkey. Here, F2 is linked to Schnyder corneal dystrophy.