CD40LG and dengue disease: However, considering the specificity of our combined antigen and antibody testing approach was determined based on a very small number (n = 30) of potentially cross-reactive samples and that there have been contrasting reports of dengue IgM and IgG ICTs having either very good specificity of >95% [30] or more moderate specificity [31], [32], an expanded study with a larger population of endemic negative samples will be required to more accurately assess the overall impact on specificity by combining both tests.