While data of Shabo and colleagues revealed that expression of the macrophage receptor CD163 on breast cancer and rectal carcinoma cells was generally associated with a poorer outcome of afflicted patients, Larsson et al. reported that syncytin expression constitutes as a positive prognostic factor in breast cancer, possibly due to mediating fusions between breast cancer cells and endothelial cells [30]. This evidence concerns the gene CD163 and breast carcinoma.