CXCR3 and rheumatoid arthritis: Recent reports have shown that the serum or tissue expressions of CXCL10 or both are increased in various autoimmune diseases like rheumatoid arthritis (RA), systemic lupus erythematosus, systemic sclerosis, and multiple sclerosis [5-8], and CXCL10 and CXCR3 may have important roles in leukocytes homing to inflamed tissues and in the perpetuation of inflammation and thus may contribute importantly to tissue damage.