BMP4 and cancer: There are a number of important cancer-related genes located on this chromosome, including Anxa7 (annexin 7, its human counterpart ANXA7 located on HSA10q21), which is a tumor suppressor gene associated with prostate cancer [37] and Bmp4, Lgals3 and Cdkn3, whose human counterparts are located on chromosome band 14q22 in human.