While cancer cell-associated VEGF was higher in the AT1RHI tumours (P ≤ 0.0123, t-test), the number of intense-staining infiltrating cells was highest in the AT1RLOW tumours and this was decreased by irbesartan treatment (P = 1.109 x 10-5) (Figure 6B). The gene discussed is VEGFA; the disease is neoplasm.