R0 patients with high PAI-1/uPAR-del4/5 (n = 30) revealed a significant 19-fold increased risk of tumor-related death (RR = 19.1, 95%CI = 1.1-335.3, P = 0.044) compared to R0 patients who showed low PAI-1/uPAR-del4/5 mRNA expression levels (n = 13). Here, PLAUR is linked to neoplasm.