ANK3 and major depressive disorder: Our data support findings from two meta-analyses of GWA-studies searching for common risk variants in ANK3 for schizophrenia, bipolar disorder or unipolar depression: One study combining Meta-analysis and additional genotyping of a bipolar and unipolar sample from the US, the UK, Ireland, and Netherlands, found no association of variants in ANK3 and unipolar depression.