A dose of 50 ng/ml IGF-1 stimulated neoplastic growth to a similar extent as MØCM (Figure 7A-D); 2 ng/mL IGF is the reported EC50 for IGF-1 stimulated proliferation in vitro as well as the concentration detected in the BALF of tumor-bearing mice in vivo (Figure 6A). Here, IGF1 is linked to neoplasm.