However, the discrepancy observed between Xue et al and our study for the Chinese population could be explained by the relatively small samples size (RA patients, n = 81) and by the fact that not all SE alleles (e.g not DRB1*01 and DRB1*10) were considered in the analysis [10], [20]. The gene discussed is HLA-DRB1; the disease is rheumatoid arthritis.